Misc - Chromatography Online
Misc

The Year of the Laser

September 1, 2010

On the 50th anniversary of the invention of the laser, Michael Balogh examines its importance in MS practice.

Biosimilars: Introduction, Concerns, and Opportunities

August 1, 2010

The authors provide an introduction to the topic of biosimilars, review the available regulatory guidance, and discuss the various scientific challenges that are present.

A Modular Approach to Pressurized Liquid Extraction with In-Cell Cleanup

July 1, 2010

A modification of the popular PLE technique is discussed.

ASMS 2010 Review

June 1, 2010

Associate Editor Megan Evans reviews this year's ASMS Conference, held in Salt Lake City, Utah.

New Horizons in RP Chromatography

June 1, 2010

We focus on the characterization of reversed-phase columns with particular emphasis on the hydrophobic-subtraction model

SPME with GCxGC and GCxGC–TOF-MS

May 1, 2010

In this article, the combination of SPME with GCxGC and GCxGC–TOF-MS is discussed using mixtures of solvents as example analytes

Column Developments for SFC

May 1, 2010

The authors review the requirements for columns specifically designed and manufactured for SFC.

Green Light for Green Chromatography?

May 1, 2010

Pat Sandra and his team will discuss how green chromatography works in practice

Is HILIC Changing the HPLC Scene?

April 27, 2010

The separation of polar and hydrophilic compounds can be a challenge. Hydrophilic interaction liquid chromatography has proven to be a solid alternative for such applications.

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LCGC COLUMNISTS 2014

Column Watch: Ron Majors, established authority on new column technologies, keeps readers up-to-date with new sample preparation trends in all branches of chromatography and reviews developments. LATEST: When Bad Things Happen to Good Food: Applications of HPLC to Detect Food Adulteration


Perspectives in Modern HPLC: Michael W. Dong is a senior scientist in Small Molecule Drug Discovery at Genentech in South San Francisco, California. He is responsible for new technologies, automation, and supporting late-stage research projects in small molecule analytical chemistry and QC of small molecule pharmaceutical sciences. LATEST: HPLC for Characterization and Quality Control of Therapeutic Monoclonal Antibodies


MS — The Practical Art: Kate Yu brings her expertise in the field of mass spectrometry and hyphenated techniques to the pages of LCGC. In this column she examines the mass spectrometric side of coupled liquid and gas-phase systems. Troubleshooting-style articles provide readers with invaluable advice for getting the most from their mass spectrometers. LATEST: Radical Mass Spectrometry as a New Frontier for Bioanalysis


LC Troubleshooting: LC Troubleshooting sets about making HPLC methods easier to master. By covering the basics of liquid chromatography separations and instrumentation, John Dolan is able to highlight common problems and provide remedies for them. LATEST: How Much Can I Inject? Part I: Injecting in Mobile Phase


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